Juvenile Nasopharyngeal Angiofibroma: Difference between revisions

Revision as of 02:24, 17 November 2024

Overview

Juvenile nasopharyngeal angiofibroma (JNA) is a benign vascular neoplasm of the nasal cavity and nasopharynx that classically presents in adolescent boys.

Pathophysiology

Relevant Anatomy

Disease Etiology

Genetics

Histology

Diagnosis

Patient History

Physical Examination

Laboratory Tests

Imaging

[Text about imaging choices]

There are several classifications for JNAs based on imaging findings.

Chandler Classification for Juvenile Nasopharyngeal Angiofibromas
Classification System	Stage I	Stage II	Stage III	Stage IV	Stage V
Andrews^[1]	Confined to NP	Invading one of the following with evidence of bony erosion: PPF, MS, ES, or SS	Invading ITF or orbit IIIa: No intracranial extension IIIb: Extradural (parasellar) extension	Intradural extension IVa: No infiltration of CS, PF, or OC IVb: Infiltration of CS, PF, or OC	--
Chandler	Confined to NP	Extension into the nasal cavity, SS, or both	Extension into any of the following: antrum, ES, PMF, ITF, orbit, or cheek	Intracranial extension	--

Differential Diagnosis

Management

Medical Management

Surgical Management

Outcomes

Complications

Prognosis

References

↑ Andrews JC, Fisch U, Aeppli U, Valavanis A, Makek MS. The surgical management of extensive nasopharyngeal angiofibromas with the infratemporal fossa approach. The Laryngoscope. 1989 Apr;99(4):429-37.

[1] Andrews JC, Fisch U, Aeppli U, Valavanis A, Makek MS. The surgical management of extensive nasopharyngeal angiofibromas with the infratemporal fossa approach. The Laryngoscope. 1989 Apr;99(4):429-37.

[1]

@@ Line 35: / Line 35: @@
 |+ Chandler Classification for Juvenile Nasopharyngeal Angiofibromas
 |-
-! Stage !! Description
+! Classification System !! style=width:15em | Stage I !! style=width:15em | Stage II !! style=width:15em | Stage III !! style=width:15em | Stage IV !! style=width:15em | Stage V
 |-
-| I || Tumor confined to the nasopharynx
+| Andrews<ref>Andrews JC, Fisch U, Aeppli U, Valavanis A, Makek MS. The surgical management of extensive nasopharyngeal angiofibromas with the infratemporal fossa approach. The Laryngoscope. 1989 Apr;99(4):429-37.</ref> || Confined to NP || Invading one of the following with evidence of bony erosion: PPF, MS, ES, or SS || Invading ITF or orbit<br>'''IIIa''': No intracranial extension<br>'''IIIb''': Extradural (parasellar) extension || Intradural extension<br>'''IVa''': No infiltration of CS, PF, or OC<br>'''IVb''': Infiltration of CS, PF, or OC || --
 |-
-| II || Tumor extension into the nasal cavity, sphenoid sinus, or both
+| Chandler || Confined to NP || Extension into the nasal cavity, SS, or both || Extension into any of the following: antrum, ES, PMF, ITF, orbit, or cheek || Intracranial extension || --
-|-
-| III || Tumor extension into one or more of the following: antrum, ethmoid sinus, pterygomaxillary or infratemporal fossa, orbit, or cheek
-|-
-| IV || Intracranial extension
-|}
-The UPMC classification system is slightly different from the Chandler system:
-{| class="wikitable", style="margin-left: auto; margin-right: auto; border: none; text-align: center"
-|+ UPMC Classification for Juvenile Nasopharyngeal Angiofibromas<ref>Andrews JC, Fisch U, Aeppli U, Valavanis A, Makek MS. The surgical management of extensive nasopharyngeal angiofibromas with the infratemporal fossa approach. The Laryngoscope. 1989 Apr;99(4):429-37.</ref>
-|-
-! Stage !! Description
-|-
-| I || Tumor limited to the nasopharynx and nasal cavity. Bone destruction negligible or limited to the sphenopalatine foramen.
-|-
-| II ||
-|-
-| IIIa ||
-|-
-| IIIb || Intracranial extension
-|-
-| IVa || Intracranial extension
-|-
-| IVb || Intracranial extension
 |}