Juvenile Nasopharyngeal Angiofibroma

Overview

Juvenile nasopharyngeal angiofibroma (JNA) is a benign vascular neoplasm of the nasal cavity and nasopharynx that classically presents in adolescent boys.

Pathophysiology

Relevant Anatomy

Disease Etiology

Genetics

Histology

Diagnosis

Patient History

Physical Examination

Laboratory Tests

Imaging

[Text about imaging choices]

There are several classifications for JNAs based on imaging findings.

Chandler Classification for Juvenile Nasopharyngeal Angiofibromas
Stage	Description
I	Tumor confined to the nasopharynx
II	Tumor extension into the nasal cavity, sphenoid sinus, or both
III	Tumor extension into one or more of the following: antrum, ethmoid sinus, pterygomaxillary or infratemporal fossa, orbit, or cheek
IV	Intracranial extension

The UPMC classification system is slightly different from the Chandler system:

UPMC Classification for Juvenile Nasopharyngeal Angiofibromas^[1]
Stage	Description
I	Tumor limited to the nasopharynx and nasal cavity. Bone destruction negligible or limited to the sphenopalatine foramen.
II
IIIa
IIIb	Intracranial extension
IVa	Intracranial extension
IVb	Intracranial extension

Differential Diagnosis

Management

Medical Management

Surgical Management

Outcomes

Complications

Prognosis

References

↑ Andrews JC, Fisch U, Aeppli U, Valavanis A, Makek MS. The surgical management of extensive nasopharyngeal angiofibromas with the infratemporal fossa approach. The Laryngoscope. 1989 Apr;99(4):429-37.

[1] Andrews JC, Fisch U, Aeppli U, Valavanis A, Makek MS. The surgical management of extensive nasopharyngeal angiofibromas with the infratemporal fossa approach. The Laryngoscope. 1989 Apr;99(4):429-37.

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