Juvenile Nasopharyngeal Angiofibroma

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Overview

Juvenile nasopharyngeal angiofibroma (JNA) is a benign vascular neoplasm of the nasal cavity and nasopharynx that classically presents in adolescent boys.

Pathophysiology

Relevant Anatomy

Disease Etiology

Genetics

Histology

Diagnosis

Patient History

Physical Examination

Laboratory Tests

Imaging

[Text about imaging choices]

There are several classifications for JNAs based on imaging findings.

Chandler Classification for Juvenile Nasopharyngeal Angiofibromas
Classification System Stage I Stage II Stage III Stage IV Stage V
Andrews[1] Confined to NP Invading one of the following with evidence of bony erosion: PPF, MS, ES, or SS Invading ITF or orbit
IIIa: No intracranial extension
IIIb: Extradural (parasellar) extension
Intradural extension
IVa: No infiltration of CS, PF, or OC
IVb: Infiltration of CS, PF, or OC
--
Chandler Confined to NP Extension into the nasal cavity, SS, or both Extension into any of the following: antrum, ES, PMF, ITF, orbit, or cheek Intracranial extension --

Differential Diagnosis

Management

Medical Management

Surgical Management

Outcomes

Complications

Prognosis

References

  1. Andrews JC, Fisch U, Aeppli U, Valavanis A, Makek MS. The surgical management of extensive nasopharyngeal angiofibromas with the infratemporal fossa approach. The Laryngoscope. 1989 Apr;99(4):429-37.