Orbital Apex Syndrome

Orbital Apex Syndrome
Other Names	Jacod Syndrome
Contents of the posterior orbit affected by Orbital Apex Syndrome
Identifiers
ICD-9	437.6
ICD-10	I67.6
Outside Resources
EyeWiki	Orbital Apex Syndrome
Radiopaedia	Orbital Apex Syndrome

Diagnosis

Differential Diagnosis

While the cause of orbital apex syndrome can vary, its presentation is similar to two other diagnoses to consider:

• Superior Orbital Fissure Syndrome
• Cavernous Sinus Syndrome

This table helps outline the differences in cranial nerve involvement in these three diagnoses.

Cranial Nerve Involvement in Diseases Near the Orbital Apex

Syndrome	CN II	CN III	CN IV	CN V-1	CN V-2	CN VI	Sympathetics
Orbital Apex Syndrome	✔	✔	✔	±		✔
Superior Orbital Fissure Syndrome		✔	✔	✔		✔
Cavernous Sinus Syndrome		✔	✔	✔	✔		✔